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In bodybuilding, Nolvadex (Tamoxifen Citrate) is used as both an anabolic steroid cycle ancillary drug and as recovery or as a post anabolic steroid cycle therapy drug. A meta-analysis published in 2011 showed that although Nolvadex is no more effective as testosterone than either anabolic steroids or HGH, it is a moderately more effective anabolic at improving muscle size than anabolic steroids and anabolic HGH and significantly improves strength more than anabolic steroids, and is associated with reduced body fat gain. It is a slightly more expensive anabolic than HGH and anabolic steroids. 4 Interactions with Hormones 4.1. Testosterone Nolvadex has been shown to attenuate the increase in testosterone induced by testosterone supplementation and is a strong activator of Testosterone receptors. It has been suggested that the increase in Testosterone (and testosterone binding globulin) occurs through the activation of testosterone receptors but the exact mechanism of action of nolvadex is uncertain. However, it should be noted that this increase occurs secondary to a reduction in estrogen, and with HGH and some other agents that promote estrogen release, the reduction in estrogen might act to preserve sexual function. The mechanism by which nolvadex improves sexual performance (and perhaps performance associated with growth hormone production) is also not understood. It may be via a suppression of estrogen due to the effect on testicular cells, but the exact and mechanistic mechanism are not known yet 4.2. Injectables A study in men on HGH injections found that those receiving a placebo were able to increase maximal strength and power and muscle size in a moderate dose-dependent fashion (with an increase in both power and maximal strength) whilst those on the combination of the two doses noted a very significant increase in strength and body mass in a dose-dependent manner (with increase in power occurring at a dose of 16mg and increase in muscle weight occurring at a dose of 3-4mg). No other effects were noted other than the increase in muscle mass noted which increased maximal strength and size for both groups (not significant). Studies investigating the effect of nolvadex on human muscle size are typically either extremely small or lack sufficient sample size and duration for generalization to other species. This may be due to the fact that only an unknown proportion of the available population of athletes have the required conditions to develop the potential benefits of nolvadex 5 Fat Mass and Similar articles: